Cosmetic purpose, not medical advice. NovaBeautix does not provide any clinical or medical indication. These sources support cosmetic care suggestions; they do not make a suggestion suitable for every person, and they do not guarantee a result. If you have an allergy, a skin condition, or any other clinical situation, talk to a physician or dermatologist before following a suggestion. See our Privacy Policy (section 4B) and Terms of Service.
Peer-reviewed studies
- A Cohort Study Using a Facial Cleansing Brush With Acne Cleansing Brush Head and a Gel Cleanser in Subjects With Mild-to-Moderate Acne and Acne-Prone Skin (Gold MH, et al.) — Journal of Drugs in Dermatology, 2019
- A Controlled Trial to Determine the Efficacy of Red and Near-Infrared Light Treatment in Patient Satisfaction, Reduction of Fine Lines, Wrinkles, Skin Roughness, and Intradermal Collagen Density Increase (Wunsch A, Matuschka K.) — Photomedicine and Laser Surgery, 2014
- Association between domestic water hardness, chlorine, and atopic dermatitis risk in early life: A population-based cross-sectional study (Perkin MR, et al.) — Journal of Allergy and Clinical Immunology, 2016
- Clinical Study to Evaluate the Efficacy and Safety of Home-used LED and IRED Mask for Crow's Feet: A Multicenter, Randomized, Double-Blind, Sham-Controlled Study (Park SH, Park SO, Jung JA) — Medicine (Baltimore) / Wolters Kluwer — Hanyang University, Seoul National University Hospital, 2025
- Efficacy and Safety of 590 Nm and 590/630 Nm Light-Emitting Diode Therapy for Sensitive Skin: A Prospective Randomized Controlled Trial (He X, He M, Wang X, et al.) — Photodermatology, Photoimmunology & Photomedicine / Wiley, 2026
- Evaluation of Caffeine Gels on Physicochemical Characteristics and In Vivo Efficacy in Reducing Puffy Eyes (Amnuaikit T, Maneenuan D, Boonme P.) — Journal of Applied Pharmaceutical Science, 2011
- Inhibitory Effect of 505 nm Green Light Emitting Diode on Melanin Synthesis in Cellular Experiments and a Human Intervention Study (Mima Y, Yamada T, Omatsu J, et al.) — Acta Dermato-Venereologica, 2025
- Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing (Dhaliwal S, et al.) — British Journal of Dermatology, 2019
- The clinical and histological effect of home-use, combination blue-red LED phototherapy for mild-to-moderate acne vulgaris in Korean patients: a double-blind, randomized controlled trial (Kwon HH, Lee JB, Yoon JY, et al.) — British Journal of Dermatology / Seoul National University, 2013
- The effect of 2% niacinamide on facial sebum production (Draelos ZD, Matsubara A, Smiles K.) — Journal of Cosmetic Laser Therapy, 2006
- The effects of heat on skin barrier function and in vivo dermal absorption (Oliveira G, Williams AC, Guy RH.) — International Journal of Pharmaceutics (Elsevier, revisado por pares), 2014
- The efficacy of red and blue light-emitting diode phototherapy combined with oral minocycline for acne conglobata: a retrospective cohort study (Hao Y, Zou X, Gao Y, Xing L, Li C.) — Frontiers in Medicine, 2026
Review articles
Laboratory (in vitro) studies
- Low-level red LED light inhibits hyperkeratinization and inflammation induced by unsaturated fatty acid in an in vitro model mimicking acne (Li WH, Fassih A, Binner C, et al.) — Lasers in Surgery and Medicine / Johnson & Johnson Skin Research Center, 2018
Cosmetic ingredient safety assessments
- CIR Quick Reference Table (Safe/Safe-with-Qualification conclusions index) — Bisabolol entry, citing Final Report on the Safety Assessment of Bisabolol, International Journal of Toxicology 18(S3):33-40 (1999) — Cosmetic Ingredient Review (CIR), 1999
- CIR Quick Reference Table (Safe/Safe-with-Qualification conclusions index) — Niacinamide entry, citing Final Report of the Safety Assessment of Niacinamide and Niacin, International Journal of Toxicology 24(Suppl 5):1-31 (2005) — Cosmetic Ingredient Review (CIR), 2005
- Re-Review of the Safety Assessment of Ascorbic Acid and Ascorbates (memo to Expert Panel, September 2024) — Cosmetic Ingredient Review (CIR), 2005
- Safety Assessment of Alpha Hydroxy Acids as Used in Cosmetics — Cosmetic Ingredient Review (CIR), 1998
- Safety Assessment of Centella asiatica-derived Ingredients as Used in Cosmetics — Cosmetic Ingredient Review (CIR), 2015
- Safety Assessment of Ceramides as Used in Cosmetics — Cosmetic Ingredient Review (CIR), 2015
- Safety Assessment of Hyaluronates as Used in Cosmetics — Cosmetic Ingredient Review (CIR), 2023
- Safety Assessment of Myristoyl Pentapeptide-4, Palmitoyl Pentapeptide-4, and Pentapeptide-4 as Used in Cosmetics — Cosmetic Ingredient Review (CIR), 2024
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics — Cosmetic Ingredient Review (CIR), 2018
- Safety Assessment of Tripeptide-1, Hexapeptide-12, Their Metal Salts and Fatty Acyl Derivatives, and Palmitoyl Tetrapeptide-7 as Used in Cosmetics — Cosmetic Ingredient Review (CIR), 2018
Regulatory opinions
- Opinion on the safety of alpha- and beta-arbutin in cosmetic products (SCCS/1642/22) — Scientific Committee on Consumer Safety (SCCS) — European Commission, 2023
- Revision of the Scientific Opinion on Vitamin A (Retinol, Retinyl Acetate, Retinyl Palmitate) in Cosmetic Products (SCCS/1639/21) — Scientific Committee on Consumer Safety (SCCS) — European Commission, 2022
U.S. FDA monographs and labeling
- 21 CFR § 333.310 — Acne active ingredients (Code of Federal Regulations, Title 21, Volume 5, 2023 ed.) — U.S. Food and Drug Administration (FDA), 1991
- 21 CFR § 352.10 — Sunscreen active ingredients (Code of Federal Regulations, Title 21, Volume 5, 2023 ed.) — U.S. Food and Drug Administration (FDA), 1999
- FINACEA (azelaic acid) Gel, 15% — Full Prescribing Information (NDA 21470, revised 04/2015) — U.S. Food and Drug Administration (FDA), 2015
U.S. FDA device clearances
- 510(k) Summary of Safety and Effectiveness — LightStim for Acne Mini, model LS4AM (K131461) — U.S. Food and Drug Administration (FDA), 2014
- 510(k) Summary of Safety and Effectiveness — LightStim for Wrinkles, model LS1WR (K120775) — U.S. Food and Drug Administration (FDA), 2012
- 510(k) Summary of Safety and Effectiveness — NuFACE Mini Device (K133823) — U.S. Food and Drug Administration (FDA), 2014
Technical and scientific references
- NASA-STD-3001 Technical Brief OCHMO-TB-009 Rev A — Physiological Effects of Touch Temperature — NASA Office of the Chief Health & Medical Officer (OCHMO), 2023
- Water Science School — Hardness of Water (classification scale) — U.S. Geological Survey (USGS), 2019
Manufacturer instructions
- NuFACE Trinity Facial Toning Device — Instruction Manual (versão distribuída oficialmente em mynuface.com) — Carol Cole Company, 2021
Other data used in the app
- Local weather, UV index, and air quality from public services such as Open-Meteo, used only to adapt your routine to your environment.
- Geocoding of the city you enter, from OpenStreetMap-based services.
- Device specifications and usage limits from NovaBeautix’s own product documentation and manuals.
Questions about a source or a suggestion? Write to contact@novabeautix.com.